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MNK2 deficiency potentiates β-cell regeneration via translational regulation

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One-carbon metabolism stimulates β-cell regeneration a–e Single-plane

The UPR is necessary for HG-induced β-cell proliferation (related

A) Schematic diagram for assessment of beta-cell regeneration. To

MNK2 deficiency potentiates β-cell regeneration via translational regulation

In vivo screen identifies a SIK inhibitor that induces β cell proliferation through a transient UPR

A small noncoding RNA links ribosome recovery and translation control to dedifferentiation during salamander limb regeneration - ScienceDirect

Volume 18 Issue 9, September 2022

MNK2 deficiency potentiates β-cell regeneration via translational regulation

Analysis of β cells after injuries by inducible Ins2-DreER;H11-rox-tdT

Adjudin improves beta cell maturation, hepatic glucose uptake and glucose homeostasis

Deletion of carboxypeptidase E in beta cells disrupts proinsulin processing and alters beta cell identity in mice

Reinforcing one-carbon metabolism via folic acid/Folr1 promotes β-cell differentiation

Christos Karampelias (@CKarampelias) / X

Adjudin improves beta cell maturation, hepatic glucose uptake and glucose homeostasis